• Product nameAnti-UXT antibody
    See all UXT primary antibodies
  • Description
    Goat polyclonal to UXT
  • Specificityab77483 is expected to recognize both reported isoforms (NP_004173.1; NP_705582.1).
  • Tested applicationsSuitable for: IHC-P, WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Cow, Dog, Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide:


    , from an internal region of Human UXT (NP_004173.1; NP_705582.1).

  • Positive control
    • Human Kidney and Skeletal Muscle lysates.



Our Abpromise guarantee covers the use of ab77483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 20 kDa (predicted molecular weight: 18 kDa).
ELISA Use at an assay dependent concentration.


  • FunctionInvolved in gene transcription regulation. Acts in concert with the corepressor URI1 to regulate androgen receptor transcription (AR). AR N-terminus-associated coactivator which may play a role in facilitating receptor-induced transcriptional activation (PubMed:11854421). Potential component of mitochondrial-associated LRPPRC, a multidomain organizer that potentially integrates mitochondria and the microtubular cytoskeleton with chromosome remodeling (PubMed:11827465). Increasing concentrations of UXT contributes to progressive aggregation of mitochondria and cell death potentially through its association with LRPPRC (PubMed:17554592). May be a nuclear chaperone that promotes formation of the NF-kappa-B enhanceosome and which is essential for its nuclear function (PubMed:17620405). Suppresses cell transformation and it might mediate this function by interaction and inhibition of the biological activity of cell proliferation and survival stimulatory factors like MECOM (PubMed:17635584). Together with URI1, associates with chromatin to the NKX3-1 promoter region.
  • Tissue specificityUbiquitous. Expressed in prostate epithelial cells. Overexpressed in a number of tumor tissues (PubMed:16221885). Highest levels in the heart, skeletal muscle, pancreas, kidney, liver, adrenal gland, peripheral blood leukocytes, lymph node, prostate, and thyroid and the lowest levels in bladder and uterus.
  • Sequence similaritiesBelongs to the UXT family.
  • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Androgen receptor trapped clone 27 protein antibody
    • ART 27 antibody
    • ART-27 antibody
    • OTTHUMP00000023226 antibody
    • OTTHUMP00000023227 antibody
    • Protein UXT antibody
    • SKP2 associated alpha PFD 1 antibody
    • STAP1 antibody
    • Ubiquitously expressed prefoldin like chaperone antibody
    • Ubiquitously expressed transcript antibody
    • Ubiquitously expressed transcript protein antibody
    • Uxt antibody
    • UXT_HUMAN antibody
    see all

Anti-UXT antibody images

  • ab77483 (5µg/ml) staining of UXT in paraffin embedded Human Thyroid Gland following steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows staining of cystoplasm in all epithelial cells, but nuclear staining in some of them.

  • Anti-UXT antibody (ab77483) at 0.03 µg/ml + Human Kidney lysate (in RIPA buffer) at 35 µg

    Predicted band size : 18 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)
    Primary incubation was 1 hour. Detected by chemiluminescence.

References for Anti-UXT antibody (ab77483)

ab77483 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77483.
Please use the links above to contact us or submit feedback about this product.