Anti-Vaccinia Virus antibody (HRP) (ab20844)

Overview

  • Product nameAnti-Vaccinia Virus antibody (HRP)
    See all Vaccinia Virus primary antibodies
  • Description
    Rabbit polyclonal to Vaccinia Virus (HRP)
  • ConjugationHRP
  • SpecificityRecognizes purified virions. Does not cross-react with Parainfluenza (1-3), RSV, Adenovirus, Influenza A & B or HSV-1. Does not react with uninfected cells. Reactive with Lister, Wyeth, New York City and MVA strains of Vaccinia.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with Vaccinia Virus.
  • Immunogen

    Lister Strain (mixture of virions and infected cell polypeptides)

  • General notes

    IgG fraction covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is absent.

Properties

Applications

Our Abpromise guarantee covers the use of ab20844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceVaccinia virus is an Orthopoxvirus, containing double stranded DNA. Fusion protein plays an important role in the entry of enveloped virus into cells. As vaccinia virus has a wide host range, it is conceivable that certain cellular components that are ubiquitously expressed on the cell mediate virus infection. The study of the entry process, attachment, fusion and the proteins and receptors involved is complex. During vaccinia virus infection, the fusion process is attributed to the action of the 14KDa protein (A27L). The N terminus of this protein recognises heparan sulfate on the cell surface. It interacts with the negative charges of sulfates of glycosaminoglycans (GAGs). Therefore, antibodies that recognize this 14KDa protein are able to neutralize vaccinia virus infection and enable identification other viral and cellular proteins which participate in the vaccinia virus entry process.
  • Alternative names
    • A27L antibody
    • Orthopoxvirus antibody

References for Anti-Vaccinia Virus antibody (HRP) (ab20844)

ab20844 has not yet been referenced specifically in any publications.

Product Wall

I should be able to confirm whether or not this antibody can be added to our catalog today or tomorrow. If we can add it to the catalog it may take a week or so to get some stock. But once we receive the antibody we will ship it that day for overnight ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"