Overview

  • Product name
  • Description
    Goat polyclonal to VAM1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    QQVLENLTELPSS

    , corresponding to N terminal amino acids 2-14 of Human VAM1.

  • Positive control
    • HEK293 Lysate and Human Brain lysates.
  • General notes
    GenBank Accession Number – NP_057531.


    Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like, ZO1-like, p55-like and LIN2-like, based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris-saline. pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Primary antibody notes
    Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like, ZO1-like, p55-like and LIN2-like, based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab5995 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 55-60 kDa (predicted molecular weight: 62 kDa).

Target

  • Tissue specificity
    Abundant in testis, brain, and kidney with lower levels detectable in other tissues.
  • Sequence similarities
    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 2 L27 domains.
    Contains 1 PDZ (DHR) domain.
    Contains 1 SH3 domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • MAGUK p55 subfamily member 6 antibody
    • MAGUK p55 subfamily member 6 VELI associated MAGUK 1 antibody
    • MAGUK protein p55T antibody
    • Membrane protein palmitoylated 6 antibody
    • Mpp6 antibody
    • MPP6_HUMAN antibody
    • p55T antibody
    • Palmitoylated 6 MAGUK p55 subfamily member 6 antibody
    • PALS2 antibody
    • Protein associated with Lin7 2 antibody
    • VAM-1 antibody
    • VELI associated MAGUK 1 antibody
    • Veli-associated MAGUK 1 antibody
    see all

Images



  • Predicted band size : 62 kDa


    ab5995 at 0.5µg/ml staining approximately 55-60kDa band of VAM1 in HEK293 Lysate by Western blot (ECL).

References

ab5995 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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