General notesab94103 is a 293T cell transfected lysate in which Human VAMP8 has been transiently over-expressed using a pCMV-VAMP8 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundFunction: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.
Tissue specificity: Platelets.
Similarity: Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.