Overview

  • Product nameAnti-VANGL2 antibody
    See all VANGL2 primary antibodies
  • Description
    Goat polyclonal to VANGL2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Xenopus laevis, Zebrafish
  • Immunogen

    Synthetic peptide:

    C-QKYLRTTKQQPYH

    , corresponding to internal sequence amino acids 403-415 of Human VANGL2

  • Positive control
    • WB: Mouse brain tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab60172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 60 kDa).

Target

  • FunctionInvolved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process.
  • Sequence similaritiesBelongs to the Vang family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Homolog of Drosophila strabismus antibody
    • KIAA1215 antibody
    • Loop tail associated protein antibody
    • loop tail protein 1 homolog antibody
    • Loop-tail protein 1 homolog antibody
    • LPP 1 antibody
    • LPP1 antibody
    • LTAP antibody
    • MGC119403 antibody
    • MGC119404 antibody
    • STB 1 antibody
    • STB1 antibody
    • STBM 1 antibody
    • STBM antibody
    • STBM1 antibody
    • Strabismus 1 antibody
    • van Gogh like protein 2 antibody
    • Van Gogh-like protein 2 antibody
    • Vang (van gogh, Drosophila) like 2 antibody
    • Vang like 2 (van gogh, Drosophila) antibody
    • vang like 2 antibody
    • vang like protein 2 antibody
    • Vang-like protein 2 antibody
    • VANG2_HUMAN antibody
    • VANGL 2 antibody
    • VANGL planar cell polarity protein 2 antibody
    • Vangl2 antibody
    see all

Anti-VANGL2 antibody images

References for Anti-VANGL2 antibody (ab60172)

This product has been referenced in:
  • Li H  et al. miR-542-3p overexpression is associated with enhanced osteosarcoma cell proliferation and migration ability by targeting Van Gogh-like 2. Mol Med Rep 11:851-6 (2015). WB ; Human . Read more (PubMed: 25352048) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 10 µg
Gel Running Conditions Non-reduced Non-Denaturing (Native)
Sample Zebrafish Tissue lysate - whole (whole embryo)
Specification whole embryo
Blocking step BSA as blocking agent for 24 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C
Username

Abcam user community

Verified customer

Submitted Feb 05 2015

Application Immunohistochemistry (Frozen sections)
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5%
Sample Mouse Tissue sections (Adult Female reproductive - Ovary/Oviduct/Uterus)
Specification Adult Female reproductive - Ovary/Oviduct/Uterus
Permeabilization Yes - PBST (PBS/0.1% v/v TritonX100 (sigma))
Fixative TCA
Username

Ms. Julia Watson

Verified customer

Submitted Nov 24 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"