Overview

  • Product nameAnti-VAP1 antibody [174-5]
    See all VAP1 primary antibodies
  • Description
    Mouse monoclonal [174-5] to VAP1
  • Tested applicationsSuitable for: WB, IHC-Fr, Functional Studies, Flow Cyt, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Purified vessels from human peripheral lymph nodes

  • Positive control
    • Human tonsil tissue.
  • General notes


    This antibody inhibits lymphocyte infiltration in liver allograft rejection in rats.

Properties

Applications

Our Abpromise guarantee covers the use of ab81718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/50. Predicted molecular weight: 85 kDa.
IHC-Fr 1/50.
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionCell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • Tissue specificityStrongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • Sequence similaritiesBelongs to the copper/topaquinone oxidase family.
  • Post-translational
    modifications
    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all

Anti-VAP1 antibody [174-5] images

  • ab81718 at 1/50 dilution staining VAP1 in human tonsil tissue section by Immunohistochemistry (frozen sections).

References for Anti-VAP1 antibody [174-5] (ab81718)

This product has been referenced in:
  • Martelius T  et al. Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection. Am J Pathol 165:1993-2001 (2004). Read more (PubMed: 15579442) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"