• Product name
    Anti-VAP1 antibody [7-88]
    See all VAP1 primary antibodies
  • Description
    Rat monoclonal [7-88] to VAP1
  • Tested applications
    Suitable for: IHC-Fr, Functional Studies, Flow Cyt, ICC/IF, IPmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Tissue/ cell preparation of vessels from Mouse lymph nodes

  • Positive control
    • Mouse spleen Mouse VAP-1-transfected CHO cells
  • General notes

    Inhibits migration of granulocytes and monocytes in acute models of inflammation.



Our Abpromise guarantee covers the use of ab81673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/50.
Functional Studies Use at an assay dependent concentration. Antibody 7-88 (200µg) was intravenously injected which resulted in the inhibition of leukocyte trafficking in inflamed peritoneum.
Flow Cyt 1/50. ab18536-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
ICC/IF 1/50.
IP Use at an assay dependent concentration.


  • Function
    Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • Tissue specificity
    Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • Sequence similarities
    Belongs to the copper/topaquinone oxidase family.
  • Post-translational
    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all


  • ab81673 staining VAP1 in mouse muscle tissue by Immunohistochemistry (Frozen sections).


This product has been referenced in:
  • Yoshikawa N  et al. Blockade of vascular adhesion protein-1 attenuates choroidal neovascularization. Mol Vis 18:593-600 (2012). ICC/IF ; Mouse . Read more (PubMed: 22419852) »
  • Merinen M  et al. Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse. Am J Pathol 166:793-800 (2005). Flow Cyt, Functional Studies, IHC-Fr ; Mouse . Read more (PubMed: 15743791) »

See all 4 Publications for this product

Customer reviews and Q&As

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Indeed, the protocol seems to me to be intermediate in the fixation with paraffin embedded tissues, where the tissues are often fixed overnight in PFA, and with frozen sections, where t...

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