Overview

  • Product name
  • Description
    Rabbit polyclonal to VAP1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human VAP1 aa 27-190.
    Sequence:

    GRGG DGGEPSQLPH CPSVSPSAQP WTHPGQSQLF ADLSREELTA VMRFLTQRLG PGLVDAAQAR PSDNCVFSVE LQLPPKAAAL AHLDRGSPPP AREALAIVFF GRQPQPNVSE LVVGPLPHPS YMRDVTVERH GGPLQMIFNRELPQ PYHRRP VLFQEYLDID


    Database link: Q16853

  • Positive control
    • Mouse kidney, liver and heart tissue extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab187202 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 85 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function
    Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • Tissue specificity
    Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • Sequence similarities
    Belongs to the copper/topaquinone oxidase family.
  • Post-translational
    modifications
    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all

Images

  • All lanes : Anti-VAP1 antibody (ab187202) at 1/500 dilution

    Lane 1 : Mouse kidney tissue extract
    Lane 2 : Mouse liver tissue extract
    Lane 3 : Mouse heart tissue extract

    Predicted band size: 85 kDa

References

This product has been referenced in:
  • Zhang Y  et al. Hypoxia serves a key function in the upregulated expression of vascular adhesion protein-1 in vitro and in a rat model of hemorrhagic shock. Mol Med Rep 16:1189-1199 (2017). Read more (PubMed: 28627649) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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