Overview

  • Product nameVarenicline tartrate
  • Description
    Orally active partial agonist at α4β2 nicotinic receptors
  • Biological descriptionHigh affinity, subtype-selective partial agonist at α4β2 nicotinic receptors. (Ki values are 0.06 (α4β2), 240 (α3β4), 322 (α7) and 3540 nM (α1βγδ)). Full agonist at α7 receptors. Orally active.
  • Purity> 99%

Properties

  • Chemical name7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate
  • Molecular weight361.37
  • Chemical structureChemical Structure
  • Molecular formulaC13H13N3.C4H6O6
  • CAS Number375815-87-5
  • Storage instructionsStore at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overviewSoluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

  • Research areas

    References for Varenicline tartrate (ab120539)

    This product has been referenced in:

    See all 4 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120539.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"