Anti-Vasopressin antibody (ab39363)
Key features and details
- Rabbit polyclonal to Vasopressin
- Suitable for: IHC-FoFr
- Reacts with: Rat, Pig
- Isotype: IgG
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Overview
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Product name
Anti-Vasopressin antibody
See all Vasopressin primary antibodies -
Description
Rabbit polyclonal to Vasopressin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-FoFrmore details -
Species reactivity
Reacts with: Rat, Pig -
Immunogen
Full length native protein (purified)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab39363 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-FoFr |
Use at an assay dependent concentration.
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Notes |
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IHC-FoFr
Use at an assay dependent concentration. |
Target
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Relevance
Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 396995 Pig
- Entrez Gene: 24221 Rat
- SwissProt: P01183 Pig
- SwissProt: P01186 Rat
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Alternative names
- ADH antibody
- Antidiuretic hormone antibody
- Arginine vasopressin neurophysin II antibody
see all
Datasheets and documents
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Datasheet download
References (17)
ab39363 has been referenced in 17 publications.
- Sacchini S et al. Methodology and Neuromarkers for Cetaceans' Brains. Vet Sci 9:N/A (2022). PubMed: 35202291
- Gumbel JH & Hubscher CH Effect of T3 Spinal Contusion Injury on Upper Urinary Tract Function. Neurotrauma Rep 3:190-198 (2022). PubMed: 35558732
- Gumbel JH et al. Timeline of Changes in Biomarkers Associated with Spinal Cord Injury-Induced Polyuria. Neurotrauma Rep 2:462-475 (2021). PubMed: 34901942
- Kania A et al. RLN3/RXFP3 Signaling in the PVN Inhibits Magnocellular Neurons via M-like Current Activation and Contributes to Binge Eating Behavior. J Neurosci 40:5362-5375 (2020). PubMed: 32532885
- Hernández-Pérez OR et al. A Synaptically Connected Hypothalamic Magnocellular Vasopressin-Locus Coeruleus Neuronal Circuit and Its Plasticity in Response to Emotional and Physiological Stress. Front Neurosci 13:196 (2019). PubMed: 30949017