Overview

  • Product nameAnti-VAV1 antibody
    See all VAV1 primary antibodies
  • Description
    Rabbit polyclonal to VAV1
  • Specificityab47403 detects endogenous levels of total VAV protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide, non-phosphopeptide derived from human VAV around the phosphorylation site of tyrosine 174.

  • Positive control
    • Jurkat cell extract.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab47403 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 101 kDa.
ELISA 1/20000.

Target

  • FunctionCouples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
  • Tissue specificityWidely expressed in hematopoietic cells but not in other cell types.
  • Sequence similaritiesContains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • DomainThe DH domain is involved in interaction with CCPG1.
  • Post-translational
    modifications
    Phosphorylated on tyrosine residues.
  • Information by UniProt
  • Database links
  • Alternative names
    • Oncogene vav antibody
    • p95Vav antibody
    • Proto-oncogene vav antibody
    • Protooncogene vav antibody
    • VAV 1 antibody
    • VAV 1 oncogene antibody
    • VAV antibody
    • Vav proto oncogene antibody
    • VAV_HUMAN antibody
    • VAV1 antibody
    see all

Anti-VAV1 antibody images

  • All lanes : Anti-VAV1 antibody (ab47403) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with blocking peptide


    Predicted band size : 101 kDa
    Observed band size : 101 kDa

References for Anti-VAV1 antibody (ab47403)

ab47403 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"