Overview

  • Product name
    VAV3 peptide

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Sequence
      C-SGEQGTLKLPEK

Specifications

Our Abpromise guarantee covers the use of ab45613 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • FLJ40431
    • Guanine nucleotide exchange factor VAV3
    • Protein vav 3
    • Protein vav3
    • RGD1565941
    • VAV 3
    • Vav 3 guanine nucleotide exchange factor
    • VAV 3 oncogene
    • VAV 3 protein
    • VAV-3
    • Vav3
    • VAV3 oncogene
    • VAV3 protein
    • VAV3_HUMAN
    see all
  • Function
    Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
  • Sequence similarities
    Contains 1 CH (calponin-homology) domain.
    Contains 1 DH (DBL-homology) domain.
    Contains 1 PH domain.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • Information by UniProt

References

ab45613 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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