Recombinant
RabMAb

Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544)

Overview

  • Product name
    Anti-VAV3 (phospho Y173) antibody [EPR1068A]
    See all VAV3 primary antibodies
  • Description
    Rabbit monoclonal [EPR1068A] to VAV3 (phospho Y173)
  • Specificity
    This antibody only detects VAV3 phosphorylated at Tyrosine 173.
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A phospho specific peptide corresponding to residues surrounding tyrosine 173 of Human VAV3

  • Positive control
    • Jurkat cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab109544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 98 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Function
      Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
    • Sequence similarities
      Contains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 SH2 domain.
      Contains 2 SH3 domains.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ40431 antibody
      • Guanine nucleotide exchange factor VAV3 antibody
      • Protein vav 3 antibody
      • Protein vav3 antibody
      • RGD1565941 antibody
      • VAV 3 antibody
      • Vav 3 guanine nucleotide exchange factor antibody
      • VAV 3 oncogene antibody
      • VAV 3 protein antibody
      • VAV-3 antibody
      • Vav3 antibody
      • VAV3 oncogene antibody
      • VAV3 protein antibody
      • VAV3_HUMAN antibody
      see all

    Anti-VAV3 (phospho Y173) antibody [EPR1068A] images

    • All lanes : Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : Jurkat cell lysate treated with Pervanadate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 98 kDa

    References for Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544)

    This product has been referenced in:
    • Maruyama K  et al. Bone-protective Functions of Netrin 1 Protein. J Biol Chem 291:23854-23868 (2016). Read more (PubMed: 27681594) »
    • Kovárová D  et al. Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis. Mol Cancer Res 11:1235-47 (2013). Read more (PubMed: 23938949) »

    See all 2 Publications for this product

    Product Wall

    Thank you for contacting us.


    Unfortunately, we do not know of any publications that have used this antibody at the moment. But I would like to reassure you that ab109544 is tested and guaranteed to work in WB with human samples.
    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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