Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544)

Overview

  • Product nameAnti-VAV3 (phospho Y173) antibody [EPR1068A]
    See all VAV3 primary antibodies
  • Description
    Rabbit monoclonal [EPR1068A] to VAV3 (phospho Y173)
  • SpecificityThis antibody only detects VAV3 phosphorylated at Tyrosine 173.
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    A phospho specific peptide corresponding to residues surrounding tyrosine 173 of Human VAV3

  • Positive control
    • Jurkat cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab109544 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 98 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionExchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitement by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.
    • Sequence similaritiesContains 1 CH (calponin-homology) domain.
      Contains 1 DH (DBL-homology) domain.
      Contains 1 PH domain.
      Contains 1 phorbol-ester/DAG-type zinc finger.
      Contains 1 SH2 domain.
      Contains 2 SH3 domains.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ40431 antibody
      • Guanine nucleotide exchange factor VAV3 antibody
      • Protein vav 3 antibody
      • Protein vav3 antibody
      • RGD1565941 antibody
      • VAV 3 antibody
      • Vav 3 guanine nucleotide exchange factor antibody
      • VAV 3 oncogene antibody
      • VAV 3 protein antibody
      • VAV-3 antibody
      • Vav3 antibody
      • VAV3 oncogene antibody
      • VAV3 protein antibody
      • VAV3_HUMAN antibody
      see all

    Anti-VAV3 (phospho Y173) antibody [EPR1068A] images

    • All lanes : Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : Jurkat cell lysate treated with Pervanadate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 98 kDa

    References for Anti-VAV3 (phospho Y173) antibody [EPR1068A] (ab109544)

    This product has been referenced in:
    • Kovárová D  et al. Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis. Mol Cancer Res 11:1235-47 (2013). Read more (PubMed: 23938949) »

    See 1 Publication for this product

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    Unfortunately, we do not know of any publications that have used this antibody at the moment. But I would like to reassure you that ab109544 is tested and guaranteed to work in WB with human samples.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"