Overview

  • Product name
    Anti-VCIP 135 antibody
  • Description
    Rabbit polyclonal to VCIP 135
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 955 and 1217 of VCIP 135 (Q96JH7)

  • Positive control
    • H1299 whole cell lysate; 293T, A431, HeLaS3, HepG2, MOLT4 or Raji lysates. SW480 xenograft (IHC-P)

Properties

Applications

Our Abpromise guarantee covers the use of ab97812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/5000. Predicted molecular weight: 134 kDa.
IHC-P Use at an assay dependent concentration.

Target

  • Function
    Acts as a deubiquitinating enzyme. Necessary for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER). Mediates dissociation of the ternary complex containing STX5A, NSFL1C and VCP (By similarity). Hydrolyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitin chains.
  • Sequence similarities
    Contains 1 OTU domain.
  • Cellular localization
    Endoplasmic reticulum. Golgi apparatus, Golgi stack. Associated with Golgi stacks and endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • Deubiquitinating protein VCIP135 antibody
    • DUBA3 antibody
    • KIAA1850 antibody
    • Valosin containing protein (p97)/p47 complex interacting protein 1 antibody
    • Valosin containing protein p97/p47 complex interacting protein 1 antibody
    • Valosin containing protein p97/p47 complex interacting protein p135 antibody
    • Valosin-containing protein p97/p47 complex-interacting protein 1 antibody
    • Valosin-containing protein p97/p47 complex-interacting protein p135 antibody
    • VCIP1_HUMAN antibody
    • VCIP135 antibody
    • VCP/p47 complex-interacting 135-kDa protein antibody
    • Vcpip1 antibody
    see all

Images

  • Anti-VCIP 135 antibody (ab97812) at 1/5000 dilution + H1299 whole cells lysate at 30 µg

    Predicted band size : 134 kDa
  • Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using ab97812 at 1/100 dilution.

References

ab97812 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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