Overview

  • Product nameAnti-VDAC2 antibody
    See all VDAC2 primary antibodies
  • Description
    Goat polyclonal to VDAC2
  • Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow, Dog, Pig
  • Immunogen

    Synthetic peptide

    GHKVGLALELEA

    , corresponding to C terminal amino acids 298-309 of Human VDAC2 Isoform 1.

  • Positive control
    • Human testis lysate, Human heart tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab118872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 32 kDa.
ELISA 1/64000.
IHC-P Use a concentration of 2.5 - 5 µg/ml.

Target

  • FunctionForms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
  • Tissue specificityExpressed in all tissues examined.
  • Sequence similaritiesBelongs to the eukaryotic mitochondrial porin family.
  • DomainConsists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands.
  • Cellular localizationMitochondrion outer membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • B-36 vdac antibody
    • FLJ23841 antibody
    • hVDAC2 antibody
    • OTTHUMP00000019878 antibody
    • OTTHUMP00000019879 antibody
    • OTTHUMP00000019880 antibody
    • Outer mitochondrial membrane protein porin 2 antibody
    • POR antibody
    • Porin-2 antibody
    • VDAC 2 antibody
    • VDAC-2 antibody
    • VDAC2 antibody
    • VDAC2_HUMAN antibody
    • Vdac6 antibody
    • Voltage dependent anion channel 2 antibody
    • Voltage dependent anion selective channel protein 2 antibody
    • Voltage-dependent anion-selective channel protein 2 antibody
    see all

Anti-VDAC2 antibody images

  • Immunohistochemical staining of ab118872 at 5 µg/ml staining VDAC2 in Paraffin-embedded Human heart tissue followed by biotinylated anti-Goat IgG secondary antibody, alkaline phosphatasestreptavidin and chromogen
  • Anti-VDAC2 antibody (ab118872) at 0.3 µg/ml + Human testis lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 32 kDa

References for Anti-VDAC2 antibody (ab118872)

ab118872 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Unfortunately, both VDAC1 and VDAC3 are very homologous with VDAC2. While we have not tested these antibodies specifically for cross-reactivity with VDAC1 and VDAC3, the antibodies ab37985 and ab118872 show ˜67% homology wi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"