Overview

  • Product nameAnti-VEGFB antibody [EPR4555]
    See all VEGFB primary antibodies
  • Description
    Rabbit monoclonal [EPR4555] to VEGFB
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    A synthetic peptide corresponding to residues in Human VEGFB.

  • Positive control
    • VEGFB recombinant protein
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab110649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 19 kDa (predicted molecular weight: 22 kDa).
  • Application notesIs unsuitable for ICC,IHC-P or IP.
  • Target

    • FunctionGrowth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
    • Tissue specificityExpressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    • Sequence similaritiesBelongs to the PDGF/VEGF growth factor family.
    • Post-translational
      modifications
      VEGF-B186 is O-glycosylated.
    • Cellular localizationSecreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    • Information by UniProt
    • Database links
    • FormThere are 2 isoforms produced by alternative splicing.
    • Alternative names
      • Vascular endothelial growth factor B antibody
      • VEGF B antibody
      • VEGF related factor antibody
      • VEGF-B antibody
      • VEGF-related factor antibody
      • Vegfb antibody
      • VEGFB_HUMAN antibody
      • VEGFL antibody
      • VRF antibody
      see all

    Anti-VEGFB antibody [EPR4555] images

    • Anti-VEGFB antibody [EPR4555] (ab110649) at 1/1000 dilution + VEGFB recombinant protein at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 22 kDa
      Observed band size : 19 kDa (why is the actual band size different from the predicted?)

    References for Anti-VEGFB antibody [EPR4555] (ab110649)

    ab110649 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"