Recombinant
RabMAb

Anti-VEGFB antibody [EPR4555] (ab110649)

Overview

  • Product name
    Anti-VEGFB antibody [EPR4555]
    See all VEGFB primary antibodies
  • Description
    Rabbit monoclonal [EPR4555] to VEGFB
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    A synthetic peptide corresponding to residues in Human VEGFB.

  • Positive control
    • VEGFB recombinant protein
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    A trial size is available to purchase for this antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab110649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 19 kDa (predicted molecular weight: 22 kDa).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
    • Tissue specificity
      Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    • Sequence similarities
      Belongs to the PDGF/VEGF growth factor family.
    • Post-translational
      modifications
      VEGF-B186 is O-glycosylated.
    • Cellular localization
      Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    • Information by UniProt
    • Database links
    • Form
      There are 2 isoforms produced by alternative splicing.
    • Alternative names
      • Vascular endothelial growth factor B antibody
      • Vascular endothelial growth factor-related factor antibody
      • VEGF B antibody
      • VEGF related factor antibody
      • VEGF-B antibody
      • VEGF-related factor antibody
      • Vegfb antibody
      • VEGFB_HUMAN antibody
      • VEGFL antibody
      • VRF antibody
      see all

    Images

    • Anti-VEGFB antibody [EPR4555] (ab110649) at 1/1000 dilution + VEGFB recombinant protein at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 22 kDa
      Observed band size : 19 kDa (why is the actual band size different from the predicted?)

    References

    ab110649 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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