Anti-Verotoxin 2 beta antibody [257] (ab20623)

Overview

  • Product nameAnti-Verotoxin 2 beta antibody [257]
  • Description
    Mouse monoclonal [257] to Verotoxin 2 beta
  • SpecificitySpecific for Verotoxin II - B subunit (SLT-2b). Neutralising antibody.
  • Tested applicationsSuitable for: ELISAmore details
  • Immunogen

    Purified toxoid.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: 10mM PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • Purification notes90% pure from ascites.
  • ClonalityMonoclonal
  • Clone number257
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab20623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20 - 1/200.

Target

  • RelevanceVerotoxins are produced by certain enterohaemorrhagic strains of Escherichia coli. Serotype O157:H7 has been the strain most commonly associated with large food bourne outbreaks and has been implicated in a wide spectrum of diseases including blood diarrhoea, haemorrhagic colitis and haemolytic uraemic syndrome. The main sources of infection are contaminated foods of animal origin such as meat and dairy products. Verotoxins, also called Shiga like toxins( SLT) because of their similarity to toxins produced by Shigella dysenteriae, are classified into two main categories: verotoxin 1 (VT1, SLT1, Stx1) and 2 (VT2, SLT2, Stx2). Verotoxin production is the most common criteria for the detection of this group of bacteria rather than tests for the cytopathic effect on Vero cells that gave the toxins their name. Verotoxins contain a single A subunit and multiple copies of a B subunit. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits.
  • Cellular localizationSecreted
  • Alternative names
    • Shiga like toxin II subunit B antibody
    • SLT IIb antibody
    • SLT2b antibody
    • stx2B antibody
    • stxB2 antibody
    • Verocytotoxin 2 subunit B antibody
    • Verotoxin 2 subunit B antibody
    see all

References for Anti-Verotoxin 2 beta antibody [257] (ab20623)

ab20623 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"