Anti-Vesicle docking protein p115 antibody (ab117103)

Overview

  • Product nameAnti-Vesicle docking protein p115 antibody
    See all Vesicle docking protein p115 primary antibodies
  • Description
    Rabbit polyclonal to Vesicle docking protein p115
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 931-960 of Human Vesicle docking protein p115 (Accessions: O60763, NP_003706.1)

  • Positive control
    • ZR-75-1 cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab117103 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 108 kDa.

Target

  • FunctionGeneral vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.
  • Sequence similaritiesBelongs to the VDP/USO1/EDE1 family.
    Contains 10 ARM repeats.
  • DomainComposed of a globular head, an elongated tail (coiled-coil) and a highly acidic C-terminal domain.
  • Post-translational
    modifications
    Phosphorylated in a cell cycle-specific manner; phosphorylated in interphase but not in mitotic cells. Dephosphorylated protein associates with the Golgi membrane; phosphorylation promotes dissociation.
  • Cellular localizationCytoplasm > cytosol. Golgi apparatus membrane. Recycles between the cytosol and the Golgi apparatus during interphase. During interphase, the phosphorylated form is found exclusively in cytosol; the unphosphorylated form is associated with Golgi apparatus membranes.
  • Information by UniProt
  • Database links
  • Alternative names
    • General vesicular transport factor antibody
    • General vesicular transport factor p115 antibody
    • P115 antibody
    • Protein USO1 homolog antibody
    • TAP antibody
    • Transcytosis associated protein antibody
    • Transcytosis-associated protein antibody
    • Uso1 antibody
    • USO1_HUMAN antibody
    • VDP antibody
    • Vesicle docking protein antibody
    • Vesicle-docking protein antibody
    see all

Anti-Vesicle docking protein p115 antibody images

  • Anti-Vesicle docking protein p115 antibody (ab117103) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 108 kDa

References for Anti-Vesicle docking protein p115 antibody (ab117103)

ab117103 has not yet been referenced specifically in any publications.

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