Overview

  • Product name
  • Description
    Rabbit polyclonal to VG5Q
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 60-90 of Human VG5Q (NP_060516.2).

  • Positive control
    • ZR-75-1 cell line lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab123342 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab123342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 81 kDa.

Target

  • Function
    Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.
  • Tissue specificity
    Widely expressed. Expressed in endothelial cells, vascular smooth muscle cells and osteoblasts. Expressed in umbilical vein endothelial cells and microvascular endothelial cells.
  • Involvement in disease
    Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS) [MIM:149000]. KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues.
  • Sequence similarities
    Contains 1 FHA domain.
    Contains 1 G-patch domain.
  • Cellular localization
    Cytoplasm. Secreted. Cytoplasmic in microvascular endothelial cells. Upon angiogenesis, when endothelial cell tube formation is initiated, it is secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AGGF 1 antibody
    • Aggf1 antibody
    • AGGF1_HUMAN antibody
    • Angiogenic factor VG5Q antibody
    • Angiogenic factor with G patch and FHA domains 1 antibody
    • G patch domain containing protein 7 antibody
    • G patch domain-containing protein 7 antibody
    • GPATC 7 antibody
    • GPATC7 antibody
    • GPATCH 7 antibody
    • GPATCH7 antibody
    • HSU84971 antibody
    • HUS84971 antibody
    • hVG5Q antibody
    • Vasculogenesis gene on 5q antibody
    • Vasculogenesis gene on 5q protein antibody
    • VG5Q antibody
    see all

Images

  • Anti-VG5Q antibody (ab123342) at 1/100 dilution + ZR-75-1 cell line lysates at 35 µg

    Predicted band size : 81 kDa

References

ab123342 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab123342.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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