Overview

  • Product nameAnti-VGLUT3 antibody [3D11]
    See all VGLUT3 primary antibodies
  • Description
    Mouse monoclonal [3D11] to VGLUT3
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (Human)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone number3D11
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab81870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 65 kDa.
ELISA Use at an assay dependent dilution.

Target

  • FunctionMediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
  • Tissue specificityExpressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
  • Involvement in diseaseDefects in SLC17A8 are the cause of deafness autosomal dominant type 25 (DFNA25) [MIM:605583]. DFNA25 is a form of sensorineural hearing loss. The expression of DFNA25 deafness is variable in terms of onset and rate of progression, with an age-dependent penetrance resembling an early-onset presbycusis, or senile deafness, a progressive bilateral loss of hearing that occurs in the aged.
  • Sequence similaritiesBelongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
  • Cellular localizationCytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Membrane. Cell junction > synapse > synaptosome.
  • Information by UniProt
  • Database links
  • Alternative names
    • deafness autosomal dominant 25 antibody
    • DFNA 25 antibody
    • DFNA25 antibody
    • SLC17A8 antibody
    • Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8 antibody
    • Solute carrier family 17 member 8 antibody
    • Vesicular glutamate transporter 3 antibody
    • VGLU3_HUMAN antibody
    • VGLUT 3 antibody
    • VGluT3 antibody
    see all

References for Anti-VGLUT3 antibody [3D11] (ab81870)

ab81870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"