Overview

  • Product name
    Vigabatrin
  • Description
    Irreversible inhibitor of GABA transaminase
  • Alternative names
    • γ-Vinyl-GABA
  • Biological description
    Irreversible inhibitor of GABA transaminase (GABA-T). Increases GABA concentrations in the brain. Anticonvulsant and induces neuronal plasticity in mouse models.

    Also available in simple stock solutions (ab146721) - add 1 ml of water to get an exact, ready-to-use concentration.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Wang QP  et al. Treatment of epilepsy: the GABA-transaminase inhibitor, vigabatrin, induces neuronal plasticity in the mouse retina. Eur J Neurosci 27:2177-87 (2008). Read more (PubMed: 18412635) »
  • Duboc A  et al. Vigabatrin, the GABA-transaminase inhibitor, damages cone photoreceptors in rats. Ann Neurol 55:695-705 (2004). Read more (PubMed: 15122710) »
  • Larsson OM  et al. Differential effect of gamma-vinyl GABA and valproate on GABA-transaminase from cultured neurones and astrocytes. Neuropharmacology 25:617-25 (1986). Read more (PubMed: 3092125) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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