Anti-Vitamin D Binding protein antibody [2G2] (ab23480)

Overview

  • Product nameAnti-Vitamin D Binding protein antibody [2G2]
    See all Vitamin D Binding protein primary antibodies
  • Description
    Mouse monoclonal [2G2] to Vitamin D Binding protein
  • Specificityab23480 is specific for Gc-globulin (vitamin D binding protein).
  • Tested applicationsELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native Gc-globulin isolated from human plasma

  • Positive control
    • Human plasma can be used as a positive control. The concentration of Gc-globulin in human plasma is approximately 400 µg/ml.

Properties

Applications

Our Abpromise guarantee covers the use of ab23480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
WB Use at an assay dependent dilution. Detects a band of approximately 50 kDa. (Note: In Western blotting after SDS-PAGE, HYB 249-01 reacts with Gc-globulin in both reduced as well as unreduced forms.)

Target

  • FunctionMultifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
  • Sequence similaritiesBelongs to the ALB/AFP/VDB family.
    Contains 3 albumin domains.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • DBP antibody
    • DBP/GC antibody
    • GC antibody
    • Gc globulin antibody
    • Gc-globulin antibody
    • GRD3 antibody
    • Group specific component antibody
    • Group specific component vitamin D binding protein antibody
    • Group-specific component antibody
    • hDBP antibody
    • VDB antibody
    • VDBG antibody
    • VDBP antibody
    • Vitamin D binding alpha globulin antibody
    • Vitamin D-binding protein antibody
    • VTDB_HUMAN antibody
    see all

References for Anti-Vitamin D Binding protein antibody [2G2] (ab23480)

This product has been referenced in:
  • Pottiez G  et al. Plasma proteomic profiling in HIV-1 infected methamphetamine abusers. PLoS One 7:e31031 (2012). WB ; Human . Read more (PubMed: 22359561) »
  • Bai S  et al. Proteome analysis of biomarkers in the cerebrospinal fluid of neuromyelitis optica patients. Mol Vis 15:1638-48 (2009). WB ; Human . Read more (PubMed: 19710940) »

See all 2 Publications for this product

Product Wall

Thank you for contacting us.

Full length vitamin D binding protein is used as immunogen for ab121060, ab121063 and ab23480 but we are sorry to tell that we do not have a specific epitope mapping, down to the amino acid sequence, available. The...

Read More

Thank you for your enquiry. Further to correspondence with the source of this antibody I can tell you that normal human plasma should be suitable as a positive control. The concentration of Gc-globulin in human plasma is approximately 400 µg/ml (M...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"