Overview

Description

  • Nature
    Synthetic
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      C-SYPIGEDEESESD
    • Amino acids
      502 to 514

Specifications

Our Abpromise guarantee covers the use of ab45648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

General Info

  • Alternative names
    • 1110037L13Rik
    • 9330105E13
    • MGC120477
    • MGC120478
    • MGC26538
    • MGC90556
    • MNAT
    • Monoamine neurotransmitter transporter
    • Monoamine transporter
    • OTTHUMP00000020576
    • SLC18A2
    • Solute carrier family 18 (vesicular monoamine) member 2
    • Solute carrier family 18 member 2
    • SVAT
    • SVMT
    • Synaptic vesicle amine transporter brain
    • Synaptic vesicle monoamine transporter brain
    • Synaptic vesicular amine transporter
    • VAT 2
    • VAT2
    • Vesicle monoamine transporter type 2
    • Vesicle monoamine/H+ antiporter
    • Vesicular amine transporter 2
    • Vesicular monoamine transporter 2
    • VMAT 2
    • VMAT2
    • VMAT2_HUMAN
    see all
  • Function
    Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis.
  • Sequence similarities
    Belongs to the major facilitator superfamily. Vesicular transporter family.
  • Cellular localization
    Cytoplasmic vesicle membrane.
  • Information by UniProt

References

ab45648 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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