Anti-VPS37B antibody (ab122450)
Key features and details
- Rabbit polyclonal to VPS37B
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-VPS37B antibody -
Description
Rabbit polyclonal to VPS37B -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence: IEEDTENMAE KFLDGELPLD SFIDVYQSKR KLAHMRRVKI EKLQEMVLKG QRLPQALAPL PPRLPELAPT APLPYPAP, corresponding to amino acids 117-194 of Human VPS37B
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Positive control
- Human colon tissue; RT4, U251 MG, Liver and Tonsil lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122450 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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WB |
Use a concentration of 0.04 - 0.4 µg/ml.
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Notes |
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IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
Use a concentration of 0.04 - 0.4 µg/ml. |
Target
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Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. -
Tissue specificity
Widely expressed. Expressed in macrophages and lymphocytes. -
Sequence similarities
Belongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain. -
Cellular localization
Late endosome membrane. Recruited to the endosomal membrane in a VPS4A-dependent fashion. - Information by UniProt
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Database links
- Entrez Gene: 79720 Human
- Omim: 610037 Human
- SwissProt: Q9H9H4 Human
- Unigene: 507162 Human
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Alternative names
- ESCRT-I complex subunit VPS37B antibody
- hVps37B antibody
- Vacuolar protein sorting-associated protein 37B antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab122450 has been referenced in 1 publication.
- Zhang Y et al. Proteomic Profiling of Purified Rabies Virus Particles. Virol Sin 35:143-155 (2020). PubMed: 31429011