Overview

  • Product name
    Anti-VPS37B antibody
  • Description
    Rabbit polyclonal to VPS37B
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence: IEEDTENMAE KFLDGELPLD SFIDVYQSKR KLAHMRRVKI EKLQEMVLKG QRLPQALAPL PPRLPELAPT APLPYPAP, corresponding to amino acids 117-194 of Human VPS37B

  • Positive control
    • Human colon tissue; RT4, U251 MG, Liver and Tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab122450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
  • Tissue specificity
    Widely expressed. Expressed in macrophages and lymphocytes.
  • Sequence similarities
    Belongs to the VPS37 family.
    Contains 1 VPS37 C-terminal domain.
  • Cellular localization
    Late endosome membrane. Recruited to the endosomal membrane in a VPS4A-dependent fashion.
  • Information by UniProt
  • Database links
  • Alternative names
    • ESCRT-I complex subunit VPS37B antibody
    • hVps37B antibody
    • Vacuolar protein sorting-associated protein 37B antibody
    • VP37B_HUMAN antibody
    • VPS37B antibody
    see all

Images

  • All lanes : Anti-VPS37B antibody (ab122450) at 1/250 dilution

    Lane 1 : RT4 lysate
    Lane 2 : U251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Liver lysate
    Lane 5 : Tonsil lysate
  • ab122450, at 1/50 dilution, staining VPS37B in paraffin-embedded Human colon tissue by Immunohistochemistry.

References

ab122450 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab122450.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up