Overview

  • Product nameAnti-VPS37B antibody
    See all VPS37B primary antibodies
  • Description
    Rabbit polyclonal to VPS37B
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence: IEEDTENMAE KFLDGELPLD SFIDVYQSKR KLAHMRRVKI EKLQEMVLKG QRLPQALAPL PPRLPELAPT APLPYPAP, corresponding to amino acids 117-194 of Human VPS37B

  • Positive control
    • Human colon tissue; RT4, U251 MG, Liver and Tonsil lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab122450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • FunctionComponent of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
  • Tissue specificityWidely expressed. Expressed in macrophages and lymphocytes.
  • Sequence similaritiesBelongs to the VPS37 family.
    Contains 1 VPS37 C-terminal domain.
  • Cellular localizationLate endosome membrane. Recruited to the endosomal membrane in a VPS4A-dependent fashion.
  • Information by UniProt
  • Database links
  • Alternative names
    • ESCRT-I complex subunit VPS37B antibody
    • hVps37B antibody
    • Vacuolar protein sorting-associated protein 37B antibody
    • VP37B_HUMAN antibody
    • VPS37B antibody
    see all

Anti-VPS37B antibody images

  • All lanes : Anti-VPS37B antibody (ab122450) at 1/250 dilution

    Lane 1 : RT4 lysate
    Lane 2 : U251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Liver lysate
    Lane 5 : Tonsil lysate
  • ab122450, at 1/50 dilution, staining VPS37B in paraffin-embedded Human colon tissue by Immunohistochemistry.

References for Anti-VPS37B antibody (ab122450)

ab122450 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab122450.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"