Overview

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab40851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 39 kDa.
IHC-P Use a concentration of 3 - 6 µg/ml.

Target

  • Function
    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
  • Sequence similarities
    Belongs to the VPS37 family.
    Contains 1 VPS37 C-terminal domain.
  • Cellular localization
    Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5730409F24Rik antibody
    • AU042646 antibody
    • ESCRT I complex subunit VPS37C antibody
    • ESCRT-I complex subunit VPS37C antibody
    • FLJ20847 antibody
    • hVps37C antibody
    • PML39 antibody
    • RGD1309258 antibody
    • Vacuolar protein sorting 37 homolog C (S. cerevisiae) antibody
    • Vacuolar protein sorting 37C (yeast) antibody
    • Vacuolar protein sorting 37C antibody
    • Vacuolar protein sorting associated protein 37C antibody
    • Vacuolar protein sorting-associated protein 37C antibody
    • VP37C_HUMAN antibody
    • VPS37C antibody
    see all

Images

  • Anti-VPS37C antibody (ab40851) at 0.03 µg/ml + Human Duodenum lysate (35µg protein in RIPA buffer).

    Predicted band size : 39 kDa
    Observed band size : 39 kDa
  • ab40851 at 3.8 µg/ml staining VPS37C in Human prostate tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

References

ab40851 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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