The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-VPS37C antibody (ab40851)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
ESCRT I complex subunit VPS37C
ESCRT-I complex subunit VPS37C
Vacuolar protein sorting 37 homolog C (S. cerevisiae)
Vacuolar protein sorting 37C
Vacuolar protein sorting 37C (yeast)
Vacuolar protein sorting associated protein 37C
Vacuolar protein sorting-associated protein 37C
FunctionComponent of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
Sequence similaritiesBelongs to the VPS37 family. Contains 1 VPS37 C-terminal domain.
Cellular localizationLate endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.