The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-VPS45A antibody (ab40853)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Leucocyte vacuolar protein sorting 45
Vacuolar protein sorting 45 homolog (S. cerevisiae)
Vacuolar protein sorting 45A
Vacuolar protein sorting 45A (yeast homolog)
Vacuolar protein sorting 45B (yeast)
Vacuolar protein sorting-associated protein 45
FunctionMay play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network.
Tissue specificityUbiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver.
Sequence similaritiesBelongs to the STXBP/unc-18/SEC1 family.
Cellular localizationGolgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network.