Overview

  • Product nameAnti-VRL1 antibody
    See all VRL1 primary antibodies
  • Description
    Goat polyclonal to VRL1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide:

    C-SEEDHLPLQVLQSH

    , corresponding to C terminal amino acids 743-756 of Human VRL1 (NP_035836.2).

  • Positive control
    • Rat brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab106829 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 86 kDa).

Target

  • FunctionCalcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
  • Sequence similaritiesBelongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
    Contains 6 ANK repeats.
  • Post-translational
    modifications
    N-glycosylated.
    Phosphorylated by PKA.
  • Cellular localizationCell membrane. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC12549 antibody
    • Osm 9 like TRP channel 2 antibody
    • Osm-9-like TRP channel 2 antibody
    • OTRPC2 antibody
    • Sac2b antibody
    • Stretch activated channel 2B antibody
    • Transient receptor potential cation channel subfamily V member 2 antibody
    • TRPV2 antibody
    • TRPV2_HUMAN antibody
    • Vanilloid receptor like protein 1 antibody
    • Vanilloid receptor-like protein 1 antibody
    • VRL 1 antibody
    • VRL antibody
    • VRL-1 antibody
    • VRL1 antibody
    see all

Anti-VRL1 antibody images

  • Anti-VRL1 antibody (ab106829) at 2 µg/ml + Rat brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 86 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

References for Anti-VRL1 antibody (ab106829)

ab106829 has not yet been referenced specifically in any publications.

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