Overview

  • Product nameAnti-VRL1 antibody
    See all VRL1 primary antibodies
  • Description
    Rabbit polyclonal to VRL1
  • SpecificityImmunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates high level of specificity for this antiserum. Cross reactivity: This antibody is known to react with rat. Other species have not been tested yet.
  • Tested applicationsSuitable for: IHC-Frmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide: C(744)KNSASEEDHLPLQVLQSP(761) (Rat) conjugated to KLH by a Glutaraldehyde linker.

  • General notesThis antibody is excellent for immunohistochemistry. It stains a subpopulation of neurons in the rat dorsal root ganglia. VRL 1 is also known as Vanilloid Receptor Like protein-1.

Properties

Applications

Our Abpromise guarantee covers the use of ab6182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr
  • Application notesImmunohistochemistry: 1/2,000
    Western Blot: Not tested.
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • Target

    • FunctionCalcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
    • Sequence similaritiesBelongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
      Contains 6 ANK repeats.
    • Post-translational
      modifications
      N-glycosylated.
      Phosphorylated by PKA.
    • Cellular localizationCell membrane. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC12549 antibody
      • Osm 9 like TRP channel 2 antibody
      • Osm-9-like TRP channel 2 antibody
      • OTRPC2 antibody
      • Sac2b antibody
      • Stretch activated channel 2B antibody
      • Transient receptor potential cation channel subfamily V member 2 antibody
      • TRPV2 antibody
      • TRPV2_HUMAN antibody
      • Vanilloid receptor like protein 1 antibody
      • Vanilloid receptor-like protein 1 antibody
      • VRL 1 antibody
      • VRL antibody
      • VRL-1 antibody
      • VRL1 antibody
      see all

    References for Anti-VRL1 antibody (ab6182)

    ab6182 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your phone call and I apologize for the damaged antibody that you received. The free of charge replacement vial is being sent to your attention on order reference # 99608 and you should receive this tomorrow. Please let me know if y...

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