Overview

  • Product name
    VU0155041 sodium salt (mM/ml)
  • Description
    PAM for mGluR4. 1 ml water soluble pack.
  • Biological description
    Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is water soluble and more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection.

    Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
  • Purity
    > 99%

Properties

  • Chemical name
    cis-2-(3,5-Dichlorophenylcarbamoyl)cyclohexanecarboxylic acid sodium salt
  • Molecular weight
    338.16
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C14H14Cl2NNaO3
  • PubChem identifier
    52974247
  • Storage instructions
    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in 1 ml water to give specified mM/ml concentration
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    [Na]OC(=O)C2CCCCC2C(=O)Nc1cc(Cl)cc(Cl)c1
  • Source

    Synthetic

  • Research areas

References

ab146686 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab146686.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up