Overview

  • Product name
    Anti-WASF3 antibody
  • Description
    Rabbit polyclonal to WASF3
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide derived from an internal region of Human WASF3.

  • Positive control
    • Human breast carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110739 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.
  • Tissue specificity
    Expressed in ovary and brain.
  • Sequence similarities
    Belongs to the SCAR/WAVE family.
    Contains 1 WH2 domain.
  • Domain
    Binds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain.
  • Cellular localization
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • KIAA0900 antibody
    • Protein WAVE-3 antibody
    • Protein WAVE3 antibody
    • SCAR3 antibody
    • Verprolin homology domain containing protein 3 antibody
    • Verprolin homology domain-containing protein 3 antibody
    • WASF3 antibody
    • WASF3_HUMAN antibody
    • WASP family protein member 3 antibody
    • WAVE3 antibody
    • Wiskott Aldrich syndrome protein family member 3 antibody
    • Wiskott-Aldrich syndrome protein family member 3 antibody
    see all

Images

  • Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using ab110739 at a dilution of 1/50. Right panel was also treated with blocking peptide.

References

This product has been referenced in:
  • Wu J  et al. Expression of WASF3 in patients with non-small cell lung cancer: Correlation with clinicopathological features and prognosis. Oncol Lett 8:1169-1174 (2014). IHC-P ; Human . Read more (PubMed: 25120680) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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