Overview

  • Product name
  • Description
    Rabbit polyclonal to WBSCR22
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Cat, Dog, Pig
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 236-285 (GGAFERRGIR GHQTRRFPLR MSRRGMVRKS RAWVLEKKER HRRQGREVRP) of Human WBSCR22 (NP_001189489).

  • Positive control
    • Human fetal liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab118766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 34 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Methyltransferase that may act on DNA.
  • Tissue specificity
    Strongly expressed in heart, skeletal muscle and kidney. Also expressed in spleen, liver, lung and testis.
  • Involvement in disease
    Note=WBSCR22 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR22 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
  • Sequence similarities
    Belongs to the methyltransferase superfamily.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • HASJ4442 antibody
    • HUSSY 3 antibody
    • HUSSY3 antibody
    • PP3381 antibody
    • Uncharacterized methyltransferase WBSCR22 antibody
    • WBMT antibody
    • WBS22_HUMAN antibody
    • WBSCR22 antibody
    • Williams Beuren candidate region putative methyltransferase antibody
    • Williams Beuren syndrome chromosome region 22 protein antibody
    • Williams-Beuren syndrome chromosomal region 22 protein antibody
    see all

Images

  • Anti-WBSCR22 antibody (ab118766) at 1 µg/ml + Human fetal liver lysate at 10 µg

    Predicted band size : 34 kDa

References

ab118766 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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