RelevanceThe WDR26 gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids, which are typically bracketed by gly-his and trp-asp (GH-WD). WD repeats may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene.