Overview

  • Product name
  • Description
    Rabbit polyclonal to WDR35
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    N-Terminus of Human WDR35.

  • Positive control
    • Human Testis and Human Thyroid tissues

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    May promote CASP3 activation and TNF-stimulated apoptosis.
  • Involvement in disease
    Defects in WDR35 are the cause of cranioectodermal dysplasia type 2 (CED2) [MIM:613610]. A disorder characterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include short stature, dolichocephaly, craniosynostosis, narrow thorax with pectus excavatum, short limbs, brachydactyly, joint laxity, narrow palpebral fissures, telecanthus with hypertelorism, low-set simple ears, everted lower lip, and short neck. Teeth abnormalities included widely spaced, hypoplastic and fused teeth.
  • Sequence similarities
    Contains 5 WD repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • Intraflagellar transport protein 121 homolog antibody
    • KIAA1336 antibody
    • MGC33196 antibody
    • Naofen antibody
    • WD repeat domain 35 antibody
    • WD repeat-containing protein 35 antibody
    • WDR35 antibody
    • WDR35_HUMAN antibody
    see all

Anti-WDR35 antibody images

  • Staining of Human WDR35 in a Formalin/PFA-fixed paraffin-embedded section of Human Testis using ab113771 at a concentration of 5 µg/ml.
  • Staining of Human WDR35 in a Formalin/PFA-fixed paraffin-embedded section of Human Thyroid using ab113771 at a concentration of 5 µg/ml.

References for Anti-WDR35 antibody (ab113771)

ab113771 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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