RelevanceWDR36 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. WDR36 is involved in T cell activation and is highly co-regulated with IL2. Mutations in WDR36 are associated with adult-onset primary open-angle glaucoma (POAG).
T cell activation WD repeat containing protein antibody
T cell activation WD repeat protein antibody
TA WDRP antibody
UTP 21 antibody
UTP21, S. cerevisiae, homolog of antibody
WD repeat containing protein 36 antibody
WD repeat domain 36 antibody
WDR 36 antibody
Anti-WDR36 antibody images
Immunocytochemistry/ Immunofluorescence - WDR36 antibody (ab73548)This image is courtesy of an Anonymous Abreview.
ab73548 staining WDR36 in immortalized Human trabecular meshwork cells by Immunocytochemistry/ Immunofluorescence. Cells were PFA-fixed and permeabilized in 0.5% Triton X-100 prior to blocking in 3% BSA for 45 minutes. The primary antibody was diluted 1/50 in 0.3% BSA/PBS and incubated with the sample for 2 hours. The secondary antibody was Alexa Fluor 488® conjugated goat anti-rabbit polyclonal, diluted 1/300.
Gallenberger M et al. Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet20:422-35 (2011).
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