Anti-WDR36 antibody (ab73548)
Key features and details
- Rabbit polyclonal to WDR36
- Suitable for: IHC-Fr, IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-WDR36 antibody -
Description
Rabbit polyclonal to WDR36 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Fr, IHC-P, ICC/IF, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Synthetic peptide derived from N terminal domain of human WDR36
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: Whole serum -
Concentration information loading...
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Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab73548 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-Fr |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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ICC/IF | (1) |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Relevance
WDR36 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. WDR36 is involved in T cell activation and is highly co-regulated with IL2. Mutations in WDR36 are associated with adult-onset primary open-angle glaucoma (POAG). -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 134430 Human
- Entrez Gene: 225348 Mouse
- Omim: 609669 Human
- SwissProt: Q8NI36 Human
- SwissProt: Q505Q0 Mouse
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Alternative names
- DKFZp686I1650 antibody
- GLC 1G antibody
- GLC1G antibody
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Protocols
Datasheets and documents
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Datasheet download
References (1)
ab73548 has been referenced in 1 publication.
- Gallenberger M et al. Lack of WDR36 leads to preimplantation embryonic lethality in mice and delays the formation of small subunit ribosomal RNA in human cells in vitro. Hum Mol Genet 20:422-35 (2011). ICC/IF ; Human . PubMed: 21051332