Listen in as Dr Swathi Arur, of the MD Anderson Cancer Center, discusses how the FirePlex® miRNA Discovery Panels are designed to sensitively profile individual miRNAs and overcome the limitations seen within current microarray methods.
Dr. Swathi Arur
obtained her PhD with Prof. M.K. Bhan from the All India Institute of
Medical Sciences. She undertook her post-graduate studies with Dr. David
Han, at the UCONN Health Science Center, where she spearheaded one of
the earliest efforts in deploying state-of-the-art differential
proteomics technology (LC-MS/MS coupled with ICAT) to understand how
dying cells were cleared by phagocytes. Her studies led to the discovery
of the first ‘eat-me’ signal (Annexin I) secreted by the dying
apoptotic cell, which enabled its recognition and removal by
Subsequently, Dr. Arur received a postdoctoral fellowship from the Washington University school of Medicine in St. Louis to train in the laboratory of Prof. Tim Schedl. During her postdoctoral training, Dr. Arur developed an approach that integrated bioinformatics, proteomics with the power of model-organism genetics to identify substrates of ERK – the terminal kinase of the RAS oncogenic pathway. Her studies discovered more than 30 new ERK targets and unraveled several new themes in RAS-ERK regulation.
Dr. Arur has run her research lab at the MD Anderson Cancer Center since 2010. She is a Research Scholar of the American Cancer Society, Anna Fuller Foundation, and Andrew Sabin Family Award. Her laboratory is currently funded by the National Institute of Health, Cancer Prevention and Research Institute of Texas and American Cancer Society.