Join Dr Bon-Kyoung Koo of the Cambridge Stem Cell Institute as he introduces the murine intestinal organoid as a novel model system, and discusses several genetic manipulation tools for organoids.
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Dr. Bon-Kyoung Koo is an experienced mouse geneticist actively employing the emerging organoid culture technology to study stem cell maintenance and activation in mouse and human intestinal and stomach organoid cultures.
Following his PhD, Dr. Koo joined the group of Prof. Hans Clevers at the Hubrecht Institute, KNAW, Netherlands. Here he utilised novel intestinal organoid culture system to perform in vitro genetics.
Dr. Koo is currently a principal investigator at the Cambridge Stem Cell Institute at the University of Cambridge, where he is developing novel genetic tools to further investigate how proliferating and quiescent adult epithelial stem cell populations are regulated both in homeostasis and regeneration.