Overview

  • Product nameAnti-WHIP antibody
    See all WHIP primary antibodies
  • Description
    Rabbit polyclonal to WHIP
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Monkey
  • Immunogen

    KLH conjugated synthetic peptide, correponding to a region from an internal region of the Human WHIP protein. The immunogen sequence shows 100% homology to Human WHIP (isoform 1) and WHIP2 (isoform 2).

  • Positive control
    • Human Kidney tissue

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab115534 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 72 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionFunctions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.
  • Tissue specificityUbiquitously expressed.
  • Sequence similaritiesBelongs to the AAA ATPase family.
    Contains 1 UBZ-type zinc finger.
  • Post-translational
    modifications
    Sumoylated by SUMO1 and SUMO2/3.
  • Cellular localizationNucleus. Colocalizes with WRN in granular structures in the nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • ATPase WRNIP 1 antibody
    • ATPase WRNIP1 antibody
    • bA420G6.2 antibody
    • FLJ22526 antibody
    • Putative helicase RUVBL antibody
    • RP11 420G6.2 antibody
    • Werner helicasae interacting protein 1 antibody
    • Werner helicasae interacting protein antibody
    • Werner helicase interacting protein isoform 2 antibody
    • Werner helicase-interacting protein 1 antibody
    • WRIP1_HUMAN antibody
    • WRNIP 1 antibody
    • WRNIP antibody
    • Wrnip1 antibody
    see all

Anti-WHIP antibody images

  • Human Kidney (formalin-fixed, paraffin-embedded) stained with ab115534 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-WHIP antibody (ab115534)

ab115534 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"