Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.
Belongs to the AAA ATPase family. Contains 1 UBZ-type zinc finger.
Sumoylated by SUMO1 and SUMO2/3.
Nucleus. Colocalizes with WRN in granular structures in the nucleus.