Overview

  • Product nameAnti-WHIP antibody
    See all WHIP primary antibodies
  • Description
    Rabbit polyclonal to WHIP
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Horse, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region within residues 400 and 450 of human WHIP (NP_064520.2).

  • Positive control
    • Human controls: anaplastic thyroid carcinoma, breast carcinoma, colon carcinoma, linitis plastica stomach cancer, ovarian carcinoma, prostate carcinoma, stomach adenocarcinoma. Mouse controls: mouse teratoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFunctions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.
    • Tissue specificityUbiquitously expressed.
    • Sequence similaritiesBelongs to the AAA ATPase family.
      Contains 1 UBZ-type zinc finger.
    • Post-translational
      modifications
      Sumoylated by SUMO1 and SUMO2/3.
    • Cellular localizationNucleus. Colocalizes with WRN in granular structures in the nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • ATPase WRNIP 1 antibody
      • ATPase WRNIP1 antibody
      • bA420G6.2 antibody
      • FLJ22526 antibody
      • Putative helicase RUVBL antibody
      • RP11 420G6.2 antibody
      • Werner helicasae interacting protein 1 antibody
      • Werner helicasae interacting protein antibody
      • Werner helicase interacting protein isoform 2 antibody
      • Werner helicase-interacting protein 1 antibody
      • WRIP1_HUMAN antibody
      • WRNIP 1 antibody
      • WRNIP antibody
      • Wrnip1 antibody
      see all

    Anti-WHIP antibody images

    • ab84475, at a 1/250 dilution, staining WHIP in formalin fixed, paraffin embedded human breast carcinoma section by Immunohistochemistry .
      Detection: DAB staining.
    • ab84475, at a 1/250 dilution, staining WHIP in formalin fixed, paraffin embedded mouse teratoma section by Immunohistochemistry .
      Detection: DAB staining.

    References for Anti-WHIP antibody (ab84475)

    ab84475 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84475.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"