Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab65943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45-48 kDa (predicted molecular weight: 40 kDa).

    Peptide ELISA: antibody detection limit dilution 1:128,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance
      WISP1 is a downstream regulator in the Wnt/Frizzled-signaling pathway and is associated with cell survival. WISP1 attentuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase and up-regulates the anti-apoptotic Bcl-X(L) protein. WISP1 is expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Overexpression is associated with several cancers including breast cancer and colon tumors.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • CCN 4 antibody
      • CCN family member 4 antibody
      • CCN4 antibody
      • WISP 1 antibody
      • WISP 1c antibody
      • WISP 1i antibody
      • WISP 1tc antibody
      • WISP1c antibody
      • WISP1i antibody
      • WISP1tc antibody
      • WNT 1 induced secreted protein 1 antibody
      • Wnt 1 induced secreted protein antibody
      • WNT 1 inducible signaling pathway protein 1 antibody
      • Wnt 1 signaling pathway protein 1 antibody
      • Wnt-1 inducible signaling pathway protein 1 antibody
      • WNT1 induced secreted protein 1 antibody
      • Wnt1 induced secreted protein antibody
      • WNT1 inducible signaling pathway protein 1 antibody
      • Wnt1 signaling pathway protein 1 antibody
      • WNT1-inducible-signaling pathway protein 1 antibody
      see all

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    References

    ab65943 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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