Anti-Wnt3 antibody [4F10-1D2] (ab52568)

Overview

  • Product nameAnti-Wnt3 antibody [4F10-1D2]
    See all Wnt3 primary antibodies
  • Description
    Mouse monoclonal [4F10-1D2] to Wnt3
  • SpecificityThis antibody is specific for the mid region of the WNT3 protein. It does not react with WNTs 1, 2, 4, 5, and 6.
  • Tested applicationsWB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein corresponding to an internal region of the human WNT3 protein

  • Positive control
    • WNT3 transfected 293 cells.

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: Tissue culture supernatant
  • PurityTissue culture supernatant
  • Clonality Monoclonal
  • Clone number4F10-1D2
  • IsotypeIgG1
  • Light chain typekappa
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab52568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 40 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.

Target

  • FunctionLigand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
  • Involvement in diseaseDefects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA) [MIM:273395]. Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects.
  • Sequence similaritiesBelongs to the Wnt family.
  • Cellular localizationSecreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Int 4 antibody
    • INT4 antibody
    • MGC131950 antibody
    • MGC138321 antibody
    • MGC138323 antibody
    • Proto-oncogene Int-4 homolog antibody
    • Proto-oncogene Wnt-3 antibody
    • wingless type MMTV integration site family member 3 antibody
    • Wnt 3 proto oncogene protein antibody
    • WNT 3 proto oncogene protein precursor antibody
    • wnt3 antibody
    • WNT3_HUMAN antibody
    see all

Anti-Wnt3 antibody [4F10-1D2] images

  • Anti-Wnt3 antibody [4F10-1D2] (ab52568) at 1 µg/ml + WNT3 transfected 293 cell lysate

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

References for Anti-Wnt3 antibody [4F10-1D2] (ab52568)

ab52568 has not yet been referenced specifically in any publications.

Product Wall

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"