Overview

  • Product name
  • Description
    Rabbit polyclonal to Wnt8b
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH corresponding to a region from the internal domain of Human Wnt8b.

  • Positive control
    • Human Brain, Cortex and Human Brain, Basal Nucleus of Meynert tissues

Properties

Applications

Our Abpromise guarantee covers the use of ab115532 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus.
  • Tissue specificity
    Expression is restricted to the brain, and more specifically to the forebrain.
  • Sequence similarities
    Belongs to the Wnt family.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein Wnt-8b antibody
    • Wingless related MMTV integration site 8b antibody
    • Wingless type MMTV integration site family, member 8B antibody
    • Wnt 8b antibody
    • Wnt8 b antibody
    • Wnt8b antibody
    • WNT8B_HUMAN antibody
    see all

Images

  • Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with ab115532 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Human Brain, Basal Nucleus of Meynert (formalin-fixed, paraffin-embedded) stained with ab115532 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References

ab115532 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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