Overview

  • Product name
    Anti-WRCH1 antibody - N-terminal
    See all WRCH1 primary antibodies
  • Description
    Rabbit polyclonal to WRCH1 - N-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human WRCH1 aa 1-11 (N terminal). The exact sequence is proprietary.
    Sequence:

    MPPQQGDPAFP


    Database link: Q7L0Q8

  • Positive control
    • Human Colon, Submucosal Plexus, tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.0
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 89% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab189951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
  • Tissue specificity
    Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.
  • Sequence similarities
    Belongs to the small GTPase superfamily. Rho family.
  • Cellular localization
    Cell membrane. Golgi apparatus membrane. Cell junction > focal adhesion. Cell projection > podosome. Localizes to podosomes in SRC-transformed cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARHU antibody
    • CDC42 L1 antibody
    • CDC42 like GTPase antibody
    • CDC42-like GTPase 1 antibody
    • CDC42L1 antibody
    • G28K antibody
    • GTP binding protein like 1 antibody
    • GTP binding protein SB128 antibody
    • GTP-binding protein-like 1 antibody
    • hG28K antibody
    • mG28K antibody
    • Ras homolog gene family member U antibody
    • Ras homolog gene family member U isoform CRA a antibody
    • Ras like gene family member U antibody
    • Rho GTPase like protein ARHU antibody
    • Rho GTPase-like protein ARHU antibody
    • Rho related GTP binding protein RhoU antibody
    • Rho-related GTP-binding protein RhoU antibody
    • Rhou antibody
    • RHOU_HUMAN antibody
    • Ryu GTPase antibody
    • Wnt-1 responsive Cdc42 homolog 1 antibody
    • Wnt1 responsive Cdc42 homolog antibody
    • WRCH 1 antibody
    • WRCH-1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon, submucosal plexus, tissue labeling WRCH1 with ab189951 at 10 µg/ml.

References

ab189951 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab189951.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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