Overview

  • Product name
  • Description
    Rabbit polyclonal to WSB1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Xenopus tropicalis
  • Immunogen

    Recombinant fragment corresponding to a region within amino acids 1 and 262 of Human WSB1 (Uniprot ID: Q9Y6I7)

  • Positive control
    • A549, HeLa, HepG2, HCT116 cells

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab153837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.

Target

  • Relevance
    WSB1 is a member of the WD-protein subfamily. It shares a high sequence identity to mouse and chick proteins. It contains six WD-repeats spanning most of the protein and an SOCS box in the C-terminus. It is a probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It recognizes type II iodothyronine deiodinase/DIO2. There are two named isoforms.
  • Cellular localization
    Intracellular
  • Database links
  • Alternative names
    • SOCS box containing WD protein SWiP 1 antibody
    • SWIP1 antibody
    • WD repeat and SOCS box containing 1 antibody
    • WD repeat and SOCS box containing protein 1 antibody
    • WSB 1 antibody
    see all

Images

  • Anti-WSB1 antibody (ab153837) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size: 47 kDa



    10% SDS PAGE

References

ab153837 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab153837.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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