Overview

  • Product name
  • Description
    Rabbit polyclonal to XPR1
  • Tested applications
    Suitable for: IHC-P, ICC, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human XPR1 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.01% Sodium Azide
    Constituents: PBS, pH 7.7
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Peptide immunogen affinity column
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab13291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/200.
ICC Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration. PubMed: 22479434

Target

  • Function
    May function in G-protein coupled signal transduction (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses.
  • Tissue specificity
    Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.
  • Sequence similarities
    Belongs to the SYG1 (TC 2.A.94) family.
    Contains 1 EXS domain.
    Contains 1 SPX domain.
  • Developmental stage
    Expressed in fetal liver.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ90308 antibody
    • OTTHUMP00000033084 antibody
    • OTTHUMP00000033085 antibody
    • Polytropic murine leukamia virus receptor SYG 1 antibody
    • Polytropic murine leukamia virus receptor SYG1 antibody
    • Protein SYG1 homolog antibody
    • SYG 1 antibody
    • SYG1 antibody
    • SYG1 protein antibody
    • X-receptor antibody
    • X3 antibody
    • Xenotropic and polytropic murine leukemia virus receptor X3 antibody
    • Xenotropic and polytropic retrovirus receptor antibody
    • Xenotropic and polytropic retrovirus receptor 1 antibody
    • XPR 1 antibody
    • XPR1 antibody
    • XPR1 protein antibody
    • XPR1_HUMAN antibody
    see all

Images

  • Ab13291 negatively staining Hek-293 cells, transiently transfected with non target GPCR.
  • Ab13291 positively staining Hek-293 cells, transiently transfected with recombinant XPR1.

References

This product has been referenced in:
  • Côté M  et al. Membrane fusion and cell entry of XMRV are pH-independent and modulated by the envelope glycoprotein's cytoplasmic tail. PLoS One 7:e33734 (2012). ICC/IF . Read more (PubMed: 22479434) »
  • Bhosle S  et al. Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells. J Virol 84:6288-96 (2010). Read more (PubMed: 20410264) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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