Overview

  • Product name
  • Description
    Rabbit polyclonal to XRCC2
  • Specificity
    ab58466 detects endogenous levels of total XRCC2 protein.
  • Tested applications
    Suitable for: IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from internal sequence of human XRCC2.

  • Positive control
    • IHC-P: Human lung carcinoma tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab58466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

Target

  • Function
    Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • Sequence similarities
    Belongs to the RecA family. RAD51 subfamily.
  • Post-translational
    modifications
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Cytoplasm, Cytoskeleton, Nucleus
  • Information by UniProt
  • Database links
  • Alternative names
    • DKFZp781P0919 antibody
    • DNA repair protein XRCC2 antibody
    • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
    • X ray repair cross complementing protein 2 antibody
    • X-ray repair cross-complementing protein 2 antibody
    • Xrcc2 antibody
    • XRCC2_HUMAN antibody
    see all

Anti-XRCC2 antibody images

  • Ab58466, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.

References for Anti-XRCC2 antibody (ab58466)

ab58466 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab58466.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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