Overview

  • Product nameAnti-XRCC2 antibody [EPR5149]
    See all XRCC2 primary antibodies
  • Description
    Rabbit monoclonal [EPR5149] to XRCC2
  • Tested applicationsSuitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human XRCC2.

  • Positive control
    • Human testis, HeLa, SW480, SH-SY5Y, Caco 2 and Human kidney lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab124900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa).
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • Application notesIs unsuitable for ICC,IHC-P or IP.
  • Target

    • FunctionInvolved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
    • Sequence similaritiesBelongs to the RecA family. RAD51 subfamily.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp781P0919 antibody
      • DNA repair protein XRCC2 antibody
      • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
      • X ray repair cross complementing protein 2 antibody
      • X-ray repair cross-complementing protein 2 antibody
      • Xrcc2 antibody
      • XRCC2_HUMAN antibody
      see all

    Anti-XRCC2 antibody [EPR5149] images

    • All lanes : Anti-XRCC2 antibody [EPR5149] (ab124900) at 1/10000 dilution

      Lane 1 : Human testis lysate
      Lane 2 : HeLa lysate
      Lane 3 : SW480 lysate
      Lane 4 : SH-SY5Y lysate
      Lane 5 : Caco 2 lysate
      Lane 6 : Human kidney lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 32 kDa
    • ab124900 at 1/100 dilution staining XRCC2 in permeablised HeLa cells by Flow cytometry (red). Rabbit IgG negative control antibody (green).

    References for Anti-XRCC2 antibody [EPR5149] (ab124900)

    ab124900 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab124900.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"